Renal Involvement In Children With Vesicoureteral Reflux: Are Prenatal Detection And Surgical Approaches Preventive?

�UroToday.com - A cogitation out of Italy investigated the personal effects of antenatal detection and different treatment methods on the outcome of unilateral vesicoureteral reflux. There was a retrospective study that enrolled 119 children with a mean age of 2.8 years with primary vesicoureteral reflux. Kidney growth and renal function were measured with ultrasound and DMSA scan, severally. In society to compare the ultrasound readings among patients of different ages, the comparative length index was measured as a percentage of the ratio of unilateral and the sum of bilateral nephritic length.




The group establish that in unilateral refluxing units, there was a reduction in both forefinger and office whereas the non-refluxing was increased. In the followup of these patients, they observed that the refluxing renal units had a worse index than those that were not refluxing. They saw that operative therapy of the refluxing renal unit led to a simplification in the index, merely its function always was low just stable. They also found that the outcome of the severely refluxing renal units was similar afterward both interventions. Whether the patient was diagnosed prenatally or postnatally, it did not seem to modify any renal result.




The group over that surgery showed similar renal outcomes to medical treatment in their long-term follow-up. They also over what we already know - which is a kidney that has senior high grade ebb does non respond to any therapy. In their patient population there seemed to be no difference in the outcome of these kidneys, whether they were diagnosed prenatally or postnatally.




Zaffanello M, Brugnara M, Cocchetto M, Fedrizzi M, Fanos V


Scand J Urol Nephrol. 2008 May 8:seventeen. Epub in the lead of print.
10.1080/00365590802092006




Reported by UroToday.com Medical Editor Pasquale Casale, MD



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